Pyramid Studio

A new chapter of therapeutic innovation

Pyramid studio embodies a new way of leading therapeutic innovation. It is a First-of-its-Kind, entrepreneurial-type, venture builder exclusively dedicated to fuel the pipeline of pharmaceutical companies.

Highlyseasoned entrepreneur team with a successfultrackrecord in Pharma & Biotech

Who
we are

We are a team of passionate and seasoned healthcare entrepreneurs and industry leaders with longstanding experience across the entire pharmaceutical industry (biotech, pharma, venture capital). We built biotech companies, we worked in Tech Transfer Offices, we performed drug discovery and developed drugs across all stages of development. Our goal is to simplify the innovation value chain to deliver faster therapies to patients.

Jérémie Mariau Msc
Founder & CEO

Ulrich Zuegel
Entrepreneur in Residence

Gary Phillips

MD Strategic Advisor

Joel Crouzet

PhD Strategic Advisor

Design sans titre (21)

Marie Laure Rives
Entrepreneur in Residence 

What
we do

We are bridging the gap between science and value. We scout, de-risk and advance breakthrough innovations from Europe’s top academic teams at the door of the clinic for our Pharma partners. We provide them with high-value assets focusing exclusively on Immunology & Inflammation (excluding oncology), neurological and rare diseases. Our team brings deep scientific expertise, hands-on experience, and a vast network in these fields.

We
Scout

…groundbreaking innovations using a unique streamlined process relying on our innovative business model

We
build up

…strategic R&D roadmaps to transform groundbreaking discoveries into valuable, patient-centered assets

We
collaborate

… with a broad network of KOLs, experts, CROs to challenge our plans and achieve operational excellence

We
deliver

… to our partners robust, near-to-the-clinic assets adding value to their drug portfolio

Why
Immuno-Inflammation neurological and rare diseases

Public health burden

We are dedicated to tackling some of the most challenging health conditions affecting millions worldwide. Immuno-inflammatory (I&I), neurological (CNS), and rare diseases not only impact the lives of patients but also pose significant challenges to healthcare systems globally.

Facts & Figures

Immuno-inflammatory diseases…

…such as rheumatoid arthritis, lupus, and inflammatory bowel diseases affect millions more, often leading to chronic pain, disability, and premature death. In the U.S., the economic burden of I&I diseases is estimated at $100 billion annually. I&I diseases often require complex, lifelong management, and while there are treatments, they are not always effective.

Neurological diseases…

…like Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis affect over 1 billion people globally. They can affect memory, speech, and motor skills, often leading to a gradual loss of autonomy. Their global economic cost is estimated at $2 trillion. Many CNS diseases still lack disease-modifying treatments as for example only 1 in 5 patients with multiple sclerosis are treated with FDA-approved disease-modifying therapies, showing the gap in effective treatments.

Rare diseases…

…collectively impact an estimated 350 million people worldwide with over 7,000 identified rare diseases. Currently, only about 10% of rare diseases have approved treatments.

Hope for the Future

Over the last decade, advancements in genetic therapies, biologics, and precision medicine have shown promise giving hope to patients. Pyramid Studio accompanies this movement by offering a new model of therapeutic innovation. We build drug-centric innovation hubs gathering scientists, entrepreneurs and pharmaceutical companies to better and faster bridge the gap from science to therapies for patients.

80

Types of autoimmune
diseases

1

people out of 12 worldwide affected by autoimmune diseases

3nd

cause of morbidity
in the world

$120bn

of annual expenses in the US for autoimmune diseases

What
makes us different

We offer a new business model that streamlines the traditional innovation value chain, speeding up the integration of new drugs in our partners portfolio, and the delivery of breakthrough medicines to patients. 

 

Pyramid Studio serves as a one-stop innovation hub embedding the capital and market vision of our partners (Pharma & Biotech companies) with top European academic science. Pyramid provides the other essentials: ability to turn discoveries into useful and valuable drugs, capital efficiency, agility and entrepreneurial mindset. 

A purpose-driven model

We act exclusively to fuel the pipeline of Pharmaceutical / large Biotech companies.

A focus on Immuno-inflammation, CNS and rare diseases

While our team has accumulated a solid track record in this field, it is marked by persistent high unmet medical needs and unresolved challenges. 

A unique business model

We draw interest from pharmaceutical companies by operating as a corporate venture fund. 

A fair value distribution

We attract scientists who are looking for a quicker path to reach patients and a more equitable way of sharing value. 

Which
benefits to our partners

We offer to our partners an innovative, tailored and effective alternative to traditional external innovation channels e.g. licensing and M&A.

  • An access to ground-breaking discoveries stemming out from top-notched science
  • An innovation hub structured around industry-driven relationships
  • 5 to 10 times cheaper near-to-clinic assets with the potential of breakthrough medicine
  • Reduced R&D-related financial burden thanks to a plug-and-play corporate venture firm model

#1

Integrated off-P&L venture builder

#2

Highly skilled & experienced team with proven records

#3

Tailored & Flexible R&D capabilities by-passing competition

#4

Assets acquisition 10-times cheaper than preclinical-stage M&A deals

Where
to find us